Bonica's Management of Pain by John D. Loeser, Steven H. Butler, C. Richard Chapman, Dennis

By John D. Loeser, Steven H. Butler, C. Richard Chapman, Dennis C. Turk

Bonica's administration of Pain is the "gold standard" textual content in soreness administration. this can be the 1st and simply textbook to take a entire and useful method of all components of ache administration, together with its mental concerns. From melanoma and surgical ache to visceral ache, this booklet covers illnesses, remedies, factors, and results. the 1st of 3 components covers the basic elements of discomfort, its anatomy, physiological and mental bases. the second one half addresses the options that alleviate soreness and, even though the first concentration is on analgesic block, different tools are lined. scientific impressions and observations of illnesses and issues with painful syndromes represent the 3rd a part of the booklet.

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Each regional section commences with a chapter that provides an overview of the anatomy and physiology, with particular emphasis on the nerve supply of that region. A comprehensive table summarizing the etiology and differential diagnosis of regional pains concludes the first chapter in each section and precedes the individual chapters on painful conditions involving different organ systems in that region. Such a tabular listing of diseases and differential diagnoses was a feature of the first edition of this book and proved to be a valuable feature; we have therefore continued it.

CONCLUSIONS Epidemiologic concepts can be applied to increase understanding of pain conditions. An epidemiologic approach increases understanding through addressing a set of questions. First, what are the extent and magnitude of the problem? Does a certain group of individuals suffer more or less from a given condition compared to other groups? Does variation in sickle cell disease risk among black Americans belonging to different geographic and cultural groups exist? Are these diseases or conditions occurring more or less frequently in recent times compared with the past?

Many other alkaloids have been identified and synthetic molecules constructed to mimic the naturally occurring drugs. The use of opioids has greatly expanded in the past 20 years as knowledge about receptors, endogenous opioids, and molecular biology has exploded (Chapter 84). Nonsteroidal agents also have a long history: Salicylic acid obtained from willow bark was first recognized in Western literature by Stone in the early nineteenth century. The development of synthetic nonsteroidal agents has been prodigious; they are the most commonly used group of pharmacologic agents ( Chapter 83).

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